TY - JOUR T1 - Infecciones por treponemas. Sífilis JO - Medicine VL - 12 IS - 59 PY - 2018 T2 - AU - Suso, M. Torralba González de AU - Martínez-Sanz, J. AU - Gi-Redondo, R. AU - Rodríguez-Zapata, M. SN - 03045412 M3 - 10.1016/j.med.2018.06.009 DO - 10.1016/j.med.2018.06.009 UR - https://medicineonline.eshttps://www.medicineonline.es/en-infecciones-por-treponemas-sifilis-articulo-S0304541218301586 AB - Treponemal infections. SyphilisSyphilis is a chronic bacterial infection caused by Treponema pallidum and is essentially sexually transmitted. The disease is important clinically and in terms of public health. The clinical manifestations are very varied and range from an ulcer or chancre to disseminated skin, cardiovascular, neurological, ophthalmological and joint lesions. In addition to the morbidity caused by the condition, it facilitates HIV infection and can cause sequelae in children born of infected mothers. Untreated, the disease progresses for years and can cause neurological and cardiac complications. Despite their antiquity, the principles of treatment have remained the same for decades. Diagnosis and management can occasionally be complex due to the variety of manifestations and the difficulty in interpreting serological tests. Penicillin is the standard treatment. Response to treatment is determined based on changes in the antibody titres in the months after treatment. KW - Treponema pallidum- Syphilis- Neuro syphilis - Sexually transmitted infection ER -